substance
noun
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the real physical matter of which a person or thing consists“DNA is the substance of our genes”
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a particular kind or species of matter with uniform properties“shigella is one of the most toxic substances known to man”
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the idea that is intendedmeaning
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the choicest or most essential or most vital part of some idea or experienceheart and soulcoreheartessencesuminwardnessmarrowpithnitty-grittykernelgistmeatnub
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what a communication that is about something is aboutcontentmessagesubject matter
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considerable capital (wealth or income)means
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material of a particular kind or constitution“the immune response recognizes invading substances”